We investigate the electrophysiological correlates of cognition. Our research seeks to identify the neurological bases of the cognitive impairments epilepsy patients suffer, thereby enabling the development of therapies to improve their quality of life. The Jobst Lab focuses on deficits of memory and attention, and studies the interaction between interictal epileptiform discharge activity and those cognitive functions. Our recent studies assess the therapeutic potential of targeted electrical stimulation. Dr. Jobst led a pilot study of the implantable NeuroPace, Inc. RNS® (Responsive Neurostimulator) device for seizure suppression and is a co-PI of the multi-center DARPA RAM project, which is developing a closed-loop electrical stimulation paradigm for the improvement of active memory.



Barbara C. Jobst, MD

Dr. Jobst is Section Chief of Adult Neurology and Director of the Dartmouth-Hitchcock Epilepsy Center. She has a broad experience in all sectors of patient care, including the ambulatory, inpatient, and operative settings. She is also an active academician with extramural funding. Dr. Jobst serves on the Dartmouth-Hitchcock Boards of Trustees.

Dr. Jobst came to DHMC in 1996 for her residency and has been on the faculty since 2001. She established the Intraoperative Neurophysiologic Monitoring program, where she gained experience in the operative environment. She also established the Women’s seizure clinic at DHMC and since the death of her mentor, Peter Williamson, in 2007, she assumed leadership of the Dartmouth-Hitchcock Epilepsy Center. Under her leadership the center became the only nationally recognized level 4 epilepsy center in Northern New England. She established multiple interdisciplinary clinical and research initiatives, many of them representing truly translational projects from bench to bedside. Within the epilepsy center she also worked on quality and process improvement. She is well recognized nationally and internationally for her expertise in epilepsy surgery, including responsive brain stimulation and single neuron recordings in humans. She is well published in her field. She is frequently invited as a speaker to national and international conferences, and has helped to establish an epilepsy center in Uruguay, South America. Dr. Jobst also has experience in advocacy for professional and lay organizations.

Dr. Jobst was born in Bayreuth, Germany, the festival city of Richard Wagner. She went to medical school in Erlangen-Nuernberg, Germany. She was an exchange student at Dartmouth Medical School in 1992. She completed a German residency in neurology and due to her extraordinary experience at Dartmouth she returned for an additional residency in neurology at DHMC. She completed her fellowship in epileptology, epilepsy surgery and neurophysiology at Dartmouth-Hitchcock Epilepsy Center.

Dr. Jobst is an avid alpine skier. She lives with her family in Hanover and enjoys living in beautiful Northern New England. 


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